Directions: As a dietary supplement take one (1) pack daily, for 21 straight days. On Training Days- Take it 30-45-minutes before working out. On Non-Training Days- Consume between meals. For best results "Cycle" this product, three weeks on, one week off.
Allergy Alert: Made in a GMP facility on equipment that processes milk, soy, egg, peanuts, tree nuts, fish, shellfish and wheat. Warnings: This product contains potent flavones and phytoecdysterones. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a physician prior to use if you have any medical condition. Discontinue use and consult your doctor if any adverse reactions occur. Do not use if pregnant or nursing. Not intended for use by persons under the age of 18. This product may be banned by some athletic associations. Athletes should consult with their sanctioning authority before use. Store in a cool, dry place. Protect from heat, light and moisture. Keep out of reach of children.
What is anabolic? Protein synthesis. Nitrogen retention. "Nutrient-partitioning". The all new Animal M-Stak. A natural supplement which helps boost anabolism and perfect for the classic "hardgainer" in all of us.
“I don't need bullshit supplements out there for those 110 lb. guys... I just need hardcore stuff that works. I'm a hardgainer. Not the strongest man in the gym, but I hold my own. I'm 5'8" at 230 lb. with 18" arms.Animal M-Stak helped me put on more mass and train like an animal in the gym. You guys keep up the good work and I"ll train my balls off in the gym and spread the word of Animal to everyone who asks me."
- K. Ly, San Francisco, CA
From green beginner to diehard vet, we’ve all gone through it. Skidding to a halt, our progress idles on a wretched plateau. Can’t gain another pound, workouts are stale, lifts are static. This is the hardgainer’s syndrome, and from the most slender of ectomorphs to the most muscular endomorph, we’ve all been there. Desperate to ignite new growth, we’ll try almost anything.
For those of us so dedicated to this game, these frequent moments of desperation have come to an end. The new Animal M-Stak is here, more powerful than ever, designed to obliterate plateaus and spark an explosion of raw muscle hypertrophy. Building on the legacy built by the original Animal M-Stak formula, the new Animal M-Stak has taken all of the most potent components of its predecessor and cranked it up to the next level.
Animal M-Stak has long been built on a foundation of natural anabolic flavones. These substances mimic the actions of bodybuilding pharmaceuticals, but without the harsh and undesirable side effects. Born from Eastern European athletic studies, these anabolic flavones have long been highly touted as performance enhancers capable of eliciting dramatic gains in lean muscle mass. The new Animal M-Stak formula combines the most potent of these anabolic compounds in more hearty dosages, making the long storied anabolic potential of the product all the greater.
Primary among these flavones are Beta-Ecdysterone and Methoxyisoflavone. These ingredients have the ability to shuttle nutrients toward lean mass accumulation, a process known as nutrient partitioning. Beyond this, these anabolic flavones promote enhanced protein synthesis and nitrogen retention. These are the mechanisms most crucial in the process of new muscle growth, brought about by Animal M-Stak without any hormonal manipulation.
With Animal M-Stak, you also get a mega potent anti-catabolic amino blend. With advanced forms of leucine and the other BCAAs spearheading the mixture, these aminos work from a cellular level to directly stimulate protein synthesis. Studies show that by adding leucine along with a protein/carb meal, you get even greater whole body net protein balance than just consuming protein and carbs alone. These aminos help to stimulate muscle recovery and protein synthesis via translation regulations, all through non-hormonal means. They do this by manipulating key muscle growth regulators such as mTOR, PKB, p70s6k, 4E-BP1, FOXO and MAFbx. These aminos essentially work as a signal for turning on the muscle building process, allowing increased muscle anabolism following a training session.
You also get potent insulin potentiators which work to maximize insulin production. Potent compounds such as K-R-ALA and CinnulinPF™ help your body to utilize ultra anabolic insulin both effectively and efficiently. This equates to increased uptake of glycogen and increased muscle cell volume which contributes to that full, pumped feeling when you workout.
Animal M-Stak also delivers a potent energy blend, packed with powerful, natural stimulants, which are designed to propel you through even the most grueling of training sessions. The addition of this complex, easily identifiable by its red capsule, makes Animal M-Stak perfect for pre-training, lighting that fire under your ass that we all need from time to time.
Finally, Animal M-Stak’s M-Factor transport complex works to maximize nutrient utilization to ensure all of the powerful components of the formula are processed to maximum efficacy. Using ginger root extract coupled with the ultra potent absorption enhancer bergmottin, you can be sure that the myriad growth factors in the Animal M-Stak formula are working to their full capacity and are not going to waste.
Animal M-Stak floods your system with an abundance of anabolic nutrients, switching your muscle building signals on and turning them to full blast. Combining potent flavones and sterones in hefty doses with the most anabolic of amino blends supported by an array pf cutting edge asaptogens in a single pretraining pack designed for optimum absorption, the new Animal M-Stak takes non-hormonal anabolics to a whole new level. Animal M-Stak, The Ultimate Hardgainer’s Stack, has come to turn "hardgainers" into "hard" gainers.
Abidov M, Crendal F, Grachev S, Seifulla R, Ziegenfuss T. Effect of extracts from Rhodiola rosea and Rhodiola crenulata roots on ATP content in mitochondria of skeletal muscles. Institute of Immunopathology, Russian Academy of Natural Sciences, Moscow.
Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR, and Jefferson LS. Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 51: 928-936, 2002.
Anthony JC, Lang CH, Crozier SJ, Anthony TG, MacLean DA, Kimball SR, and Jefferson LS. Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine. Am J Physiol Endocrinol Metab 282: E1092–E1101, 2002.
Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR, and Jefferson LS. Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 51: 928–936, 2002.
Baranov VB. The response of cardiovascular system to dosed physical load under the effect of herbal adaptogen. Contract 93-11-615 Phase I and Phase II. Moscow: Russian Federation Ministry of Health Institute of Medical and Biological Problems; 1994.
Bidzinska B, et al. Effect of different chronic intermittent stressors and acetyl-l-carnitine on hypothalamic beta-endorphin and GnRH and on plasma testosterone levels in male rats. Neuroendocrinology 57:985-90, 1993.
Bratusch-Marrain, et al. The influence of amino acids and somatostatin on prolactin and growth hormone release in man. Acta Endocrinol 90:403, 1979.
Brodie A. Aromatase and its inhibitors: an overview. J Steroid Biochem 40(1-3):255, 1991.
Campbell DR, Kurzer MS. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. J Steroid Biochem Mol Biol 46:381-388, 1993.
Chermnykh NS, et al. The action of metandrostenolone and ecdysterones on the physical endurance of animals and on protein metabolism in the skeletal muscles. Farmocol Toksikol 1988;51:57-60.
Dinan L. 2001, Phytoecdysteroids: biological aspects. Phytochemistry 57:325-339
DiSilverio F, et al. Evidence that serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992; 21:309.
Gadzhieva RM, et al. A comparative study of the anabolic action of ecdysten, leveton and Prime Plus, preparations of plant origin. Eksp Klin Faramkol 1995;58:46-8.
Germia E. Antioxidant actions of acetyl-l-carnitine: in vitro study. Med Sci Res 16:699-700, 1988.
Hammarqvist F, et al. Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery. Surgery 109(1):28-36, 1991.
Karlsson HK, Nilsson PA, Nilsson J, Chibalin AV, Zierath JR, and Blomstrand E. Branched-chain amino acids increase p70S6K phosphorylation in human skeletal muscle after resistance exercise. Am J Physiol Endocrinol Metab 287: E1–E7, 2004
Laszlo F, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. US Patent 4,163,746, August 7, 1979.
Mamatkhanov A. U. et al. Isolation of Turkesterone from the epigeal part of ajuga turkestanica and it’s anabolic activity. Chemistry of natural compounds, 1998, vol. 34, pp. 150-154
Nair KS, Schwartz RG, and Welle S. Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Am J Physiol Endocrinol Metab 263: E928–E934, 1992
Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutrition. 2006 Feb;136(2):533S-537S.
Otaka T, Okui S, Uchiyama M 1969, Stimulation of protein synthesis in mouse liver by ecdysone. Chemical & Pharmaceutical Bulletin (Japan) 17(1):75-81.
René Koopman, et al. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Am J Physiol Endocrinol Metab 288: E645-E653, 2005.
Sershon H, et al. Effect of acetyl-l-carnitine on the dopaminergic systems in aging animals. J Neurosci 30:555-59, 1991.
Spasov AA, et al. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 2000;7(2):85-9.
Syrov VN, et al. Anabolic activity of phytoecdysone-ecdysterone isolated from Rhaponticum carhamoides (Willd.). Farmocol Toksikol 1976;39:690-3.
Taglialagela G, et al. Acetyl-l-carnitine enhances the response of pc12 cells to nerve growth factor. Brain Res Dev Brain Res 59:221-30, 1991.
Animal Pump - The Pre-workout Muscle Volumizing Stack! ...Up The Volume!
The most complete, comprehensive creatine foundational supplement. You get a full daily dose of the most cutting-edge creatines, plus a ton of other actives including NO boosters, cell volumizers, energy complex, antioxidants–all in one convenient "pack." This baby's got it all.
"This stuff's great! Works within half an hour, not like your typical creatine supplement. Gives you a pump throughout your workout from beginning to end. Highly recommended for anyone who is serious about getting big and strong."
- Jimmy V.
The pump... It is the holy grail of bodybuilding. It is that most addictive of sensations that keeps gym rats hooked for life. It is euphoric and invigorating, an intense swelling of the muscle caused by a training-induced cascade of blood... It is a rebirth experienced on each worthwhile trip to the gym. The pump is instant gratification... An automatic reward for all of the blood, sweat and tears you spill on the gym floor. The pump is instantaneous growth... It is the immediate invigoration of dormant muscle fibers.
There are days, however, where no matter what you do, the pump is seemingly unattainable... Set after wasted set, you toil in vain. Nothing. Nada. Zilch. You yearn to be pumped and swole and instead you are beaten and weary. On other days, the pump is fleeting. As quickly as it arrives, it is gone... Leaving both your ego and your muscle bellies deflated. The disappointment in your inability to achieve and sustain the cherished pump is not merely due to the pleasure of a superficial physical response, but in the fact that an opportunity for new growth has been squandered. The pump ain't just for fun-it is crucial to getting big.
The pump is essential in the promotion of new muscle growth. With each pump-inducing rep, nutrient rich fluid and blood fills the working cells, engorging the muscle. This occurrence kick starts the anabolic process. The muscle cell walls are stretched and strained and practically bursting with fluid, this is called cell volumization. Assuming you are eating and supplementing properly, this fluid should be chock full of the kind of nourishing elements specifically designed to help you do the one thing you came here to do... Grow. This is where Animal Pump kicks down the door and goes to work.
Now ya know why you need the pump-that feeling of having your muscles fully engorged with blood is what drives a bodybuilder. Once the pump is there, fueling the muscles with the right nutrients is where optimal gains can be reached. Animal Pump is this fuel. Getting the right blend of nutrients is essential. Animal Pump has it all, from it's synergistic cutting edge creatine blend, NO Blast Complex, proprietary energy and concentration mix, down to it's cell supportive antioxidant complex and specialized transport blend which shuttles the Pump to your starving muscles.
From a strength and muscle cell volumizing point of view, it gets no better than Animal Pump, because Pump is packed with a new school matrix of creatines-a full, daily dose. Bodybuilders have used creatine for a decade now with good results and over the years, science has brought more and more advanced forms of creatine to the fore. Creatine is a core, basic bodybuilding supplement and as such, Animal Pump is a welcome addition to the Animal line.
When you perform a heavy set, intracellular ATP levels decrease. Creatine helps restore these ATP levels. But not just any old creatine will do the job; Animal Pump includes only the best. Taking creatine supplementation to the next level, Animal Pump combines Magnesium Creatine Chelate (MCC), a patented form of creatine, with the newest sensation Creatine Ethyl Ester (CEE) and Tri-Creatine Matrix (TCM) to deliver maximum benefits. This blend combats the creatine absorption issues and bloating of yesteryear, ensuring your creatine reaches your growing muscles and not the toilet bowl. Pump ensures that the ergogenic effects of creatine are maximized, eliminating any unwanted side effects and making the creatine non-responder of yesteryear an extinct species.
During an intense workout, one of the limiting factors of your muscular power and endurance is oxygen and the availability of oxygen-rich nutrients to muscle tissue. Our NO Blast Complex is a blend of compounds designed to combat this problem. From a bodybuilding point of view, this means incredible muscular pumps and a greater ability to funnel clean oxygen and nutrient-rich blood into your muscles. This results in optimal muscular fullness and cellular nutrient uptake and translates into what all bodybuilders crave-greater size gains.
Even if you are strong and pumped, how can you possibly tear the gym apart if you're energy deprived and lacking mental concentration? Daily life is filled with constant roadblocks that try to throw you off in the iron game. So when it comes to energy, Animal Pump has got your back. Animal Pump'sEnergy Rush Complex gives you that energy boost that gets you fired up for training and the focus and mental acuity so vital to establishing the mind-muscle connection. These powerful substances reach deep into the muscle cell to provide long-lasting energy and power, thus delaying the onset of muscle fatigue. That performance and focus edge can be the difference between the physique of a weekend warrior and a top competitor.
We ain't done yet, bro... Animal Pump incorporates a comprehensive antioxidant blend designed to protect your cells from the heavy onslaught of hardcore lifting. Heavy lifting leaves behind free radicals, which are damaging if left alone. Free radical production is also increased with enhanced nitric oxide release. We included the best antioxidants to make sure these free radicals are cleaned out leaving your immune system strong.
Last but certainly not least, a supreme nutrient transport complex, a blend of insulin boosters and absorption enhancers, ties the Animal Pump formula together. This complex efficiently and quickly draws all of these critical nutrients to your muscles. Insulin is especially important for channeling this powerful cutting edge blend into your muscle cells. Sugar-laden formulas of the past helped boost insulin levels, however they also added unnecessary carbohydrates.
With Animal Pump no carbs are needed for maximum insulin potentiating effects. Animal Pump's innovative insulin boosters can significantly enhance the pump, decrease lactic acid build up and rapidly saturate the muscle with cutting edge creatines and essential nutrients for growth. This is further amplified by specialized absorption enhancers, which ensure that Animal Pump's complexes are fully absorbed and transported to the muscles where they will be fully utilized.
The pump is an integral component to new muscle growth. It is literally the "lifeblood" of your bodybuilding pursuits, giving meaning to monotonous training sessions and giving nourishment to your depleted muscle cells. Without the pump, you're going nowhere... Harness its power and the sky's the limit. If you wanna blow up, with seam-tearing, stretch-marking mass and personal record breaking strength, Animal Pump is your holy grail. It's the pump, in a pack.
Animal Pump can be taken year round, without cycling off. Like Animal Pak, Animal Flex and Animal Nitro/G, Pump is designed as a core or "foundational supplement". For bigger gains, consider stacking Pump with Stak.
Brilla LR, Giroux MS, Taylor A, Knutzen KM. Magnesium-creatine supplementation effects on body water. Metabolism. 2003 Sep;52(9):1136-40
Selsby JT, DiSilvestro RA, Devor ST. Mg2+-creatine chelate and a low-dose creatine supplementation regimen improve exercise performance. J Strength Cond Res. 2004 May;18(2):311-5.
Casey A, Constantin-Teodosiu D, Howell S, Hultman E, Greenhaff PL. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans. Am J Physiol. 1996 Jul;271(1 Pt 1):E31-7.
Casey A, Greenhaff PL. Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance? Am J Clin Nutr. 2000 Aug;72(2 Suppl):607S-17S. Review.
Greenhaff PL, Casey A, Short AH, Harris R, Soderlund K, Hultman E. Influence of oral creatine supplementation of muscle torque during repeated bouts of maximal voluntary exercise in man. Clin Sci (Lond). 1993 May;84(5):565-71.
Kutz MR, Gunter MJ. Creatine monohydrate supplementation on body weight and percent body fat. J Strength Cond Res. 2003 Nov;17(4):817-21.
Rico-Sanz J, Mendez Marco MT. Creatine enhances oxygen uptake and performance during alternating intensity exercise. Med Sci Sports Exerc. 2000 Feb;32(2):379-85.
Steenge GR, Lambourne J, Casey A, Macdonald IA, Greenhaff PL. Stimulatory effect of insulin on creatine accumulation in human skeletal muscle. Am J Physiol. 1998 Dec;275(6 Pt 1):E974-9.
Escobales N, Rivera-Correa M, Altieri PI, Rodriguez JF. Relationship between NO synthesis, arginine transport, and intracellular arginine levels in vascular smooth muscle cells. Amino Acids. 2000;19(2):451-68.
Kohli R, Meininger CJ, Haynes TE, Yan W, Self JT, Wu G. Dietary L-arginine supplementation enhances endothelial nitric oxide synthesis in streptozotocin-induced diabetic rats. J Nutr. 2004 Mar;134(3):600-8.
Maxwell AJ, Ho HV, Le CQ, Lin PS, Bernstein D, Cooke JP. L-arginine enhances aerobic exercise capacity in association with augmented nitric oxide production. J Appl Physiol. 2001 Mar;90(3):933-8.
Schaefer A, Piquard F, Geny B, Doutreleau S, Lampert E, Mettauer B, Lonsdorfer J. L-arginine reduces exercise-induced increase in plasma lactate and ammonia. Int J Sports Med. 2002 Aug;23(6):403-7.
Paddon-Jones D, Borsheim E, Wolfe RR. Potential ergogenic effects of arginine and creatine supplementation. J Nutr. 2004 Oct;134(10 Suppl):2888S-2894S; discussion 2895S. Review.
Meneguello MO, Mendonca JR, Lancha AH Jr, Costa Rosa LF. Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained rats. Cell Biochem Funct. 2003 Mar;21(1):85-91.
Bucci LR, Hickson JF Jr, Wolinsky I, Pivarnik JM. Ornithine supplementation and insulin release in bodybuilders. Int J Sport Nutr. 1992 Sep;2(3):287-91.
Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone PJ. Citrulline/malate promotes aerobic energy production in human exercising muscle. Br J Sports Med. 2002 Aug;36(4):282-9.
Callis A, Magnan de Bornier B, Serrano JJ, Bellet H, Saumade R. Activity of citrulline malate on acid-base balance and blood ammonia and amino acid levels. Study in the animal and in man. Arzneimittelforschung. 1991 Jun;41(6):660-3.
Goubel F, Vanhoutte C, Allaf O, Verleye M, Gillardin JM. Citrulline malate limits increase in muscle fatigue induced by bacterial endotoxins. Can J Physiol Pharmacol. 1997 Mar;75(3):205-7.
Chan WK, Decker EA, Chow CK, Boissonneault GA. Effect of dietary carnosine on plasma and tissue antioxidant concentrations and on lipid oxidation in rat skeletal muscle. Lipids. 1994 Jul;29(7):461-6.
Mozdzan M, Szemraj J, Rysz J, Nowak D. Antioxidant properties of carnosine re-evaluated with oxidizing systems involving iron and copper ions. Basic Clin Pharmacol Toxicol. 2005 May;96(5):352-60.
Reddy VP, Garrett MR, Perry G, Smith MA. Carnosine: a versatile antioxidant and antiglycating agent. Sci Aging Knowledge Environ. 2005 May 4;2005(18):pe12.
Nikolic J, Bjelakovic G, Stojanovic I. Effect of caffeine on metabolism of L-arginine in the brain. Mol Cell Biochem. 2003 Feb;244(1-2):125-8.
Greer F, Friars D, Graham TE. Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance. J Appl Physiol. 2000 Nov;89(5):1837-44.
Kobayashi Y, Nakano Y, Kizaki M, Hoshikuma K, Yokoo Y, Kamiya T. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Planta Med. 2001 Oct;67(7):628-33.
McDaniel MA, Maier SF, Einstein GO. "Brain-specific" nutrients: a memory cure? Nutrition. 2003 Nov-Dec;19(11-12):957-75. Review.
Imai K, Nakachi K. Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ. 1995 Mar 18;310(6981):693-6.
Burke DG, Chilibeck PD, Parise G, Tarnopolsky MA, Candow DG. Effect of alpha-lipoic acid combined with creatine monohydrate on human skeletal muscle creatine and phosphagen concentration. Int J Sport Nutr Exerc Metab. 2003 Sep;13(3):294-302.
Cakatay U, Kayali R, Sivas A, Tekeli F. Prooxidant activities of alpha-lipoic acid on oxidative protein damage in the aging rat heart muscle. Arch Gerontol Geriatr. 2005 May-Jun;40(3):231-40.
Lee WJ, Song KH, Koh EH, Won JC, Kim HS, Park HS, Kim MS, Kim SW, Lee KU, Park JY. Alpha-Lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochem Biophys Res Commun. 2005 Jul 8;332(3):885-91.
Jacob S, Henriksen EJ, Schiemann AL, Simon I, Clancy DE, Tritschler HJ, Jung WI, Augustin HJ, Dietze GJ. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung. 1995 Aug;45(8):872-4.
Vinson JA, Proch J, Bose P. MegaNatural((R)) Gold Grapeseed Extract: In Vitro Antioxidant and In Vivo Human Supplementation Studies. J Med Food. 2001 Spring;4(1):17-26.
Sugisawa A, Inoue S, Umegaki K. Grape seed extract prevents H(2)O(2)-induced chromosomal damage in human lymphoblastoid cells. Biol Pharm Bull. 2004 Sep;27(9):1459-61.
Shi J, Yu J, Pohorly JE, Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food. 2003 Winter;6(4):291-9. Review.
Jayaprakasha GK, Ohnishi-Kameyama M, Ono H, Yoshida M, Jaganmohan Rao L. Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity. J Agric Food Chem. 2006 Mar 8;54(5):1672-9.
Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y. Cinnamon extract prevents the insulin resistance induced by a high-fructose diet. Horm Metab Res. 2004 Feb;36(2):119-25.
Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y. Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats. Diabetes Res Clin Pract. 2003 Dec;62(3):139-48.
Masuda Y, Kikuzaki H, Hisamoto M, Nakatani N. Antioxidant properties of gingerol related compounds from ginger. Biofactors. 2004;21(1-4):293-6.
Yamahara J, Huang QR, Li YH, Xu L, Fujimura H. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem Pharm Bull (Tokyo). 1990 Feb;38(2):430-1.
Broca C, Breil V, Cruciani-Guglielmacci C, Manteghetti M, Rouault C, Derouet M, Rizkalla S, Pau B, Petit P, Ribes G, Ktorza A, Gross R, Reach G, Taouis M. Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat. Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E463-71. Epub 2004 Apr 13.
Broca C, Gross R, Petit P, Sauvaire Y, Manteghetti M, Tournier M, Masiello P, Gomis R, Ribes G. 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties. Am J Physiol. 1999 Oct;277(4 Pt 1):E617-23.
Sauvaire Y, Petit P, Broca C, Manteghetti M, Baissac Y, Fernandez-Alvarez J, Gross R, Roye M, Leconte A, Gomis R, Ribes G. 4-Hydroxyisoleucine: a novel amino acid potentiator of insulin secretion. Diabetes. 1998 Feb;47(2):206-10.
Chun H, Shin DH, Hong BS, Cho WD, Cho HY, Yang HC. Biochemical properties of polysaccharides from black pepper. Biol Pharm Bull. 2002 Sep;25(9):1203-8.
Khajuria A, Thusu N, Zutshi U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine. 2002 Apr;9(3):224-31.
Note: We recommend you consult a physician or nutritionist if you have any questions regarding the use of this product. Nutritional information may vary depending on flavour.
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